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FACT-HN-RAD Functional Assessment of Cancer Therapy – Head & Neck Radiotherapy Index For patients with Head & Neck cancer undergoing radiotherapy LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview The FACT-HN-RAD captures the most common patient- and physician-reported adverse events related to radiotherapy for patients with head and neck cancer, as well as providing a way to monitor patient-reported treatment-related adverse events and recovery over time in both clinical and research settings. MEASURE NAME: Functional Assessment of Cancer Therapy – Head & Neck Radiotherapy Index (FACT-HN-RAD) VERSION: 1 NUMBER OF ITEMS: 8 PATIENT POPULATION: Head & neck cancer patients 18 years and older undergoing radiotherapy treatment RECALL PERIOD: Past 7 days RESPONSE SCALE: 5 point Likert-type scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: Radiotherapy index TIME FOR COMPLETION: Less than 5 minutes SCORING: Manual scoring template, some items are reverse scored. RELATED MEASURES: FHNSI , NFHNSI-22 , FACT-HN DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the FACT-HN-RAD can be obtained by registering for permission. Users are not permitted to translate the FACT-HN-RAD without permission from FACIT.org. Permission from FACIT.org to translate the FACT-HN-RAD may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Gharzai LA, Mierzwa ML, Peipert JD, Kirtane K, Casper K, Yadav P, Rothrock N, Cella D, Shaunfield S. Monitoring Adverse Effects of Radiation Therapy in Patients With Head and Neck Cancer: The FACT-HN-RAD Patient-Reported Outcome Measure. JAMA Otolaryngol Head Neck Surg . 2023 Oct 1;149(10):884-890. doi: 10.1001/jamaoto.2023.2177. PMID: 37589994; PMCID: PMC10436187. Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 1996; 5: 309-320. Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232. Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85. Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191. LICENSE THIS MEASURE Related Measures Related Measures FHNSI Functional Assessment of Cancer Therapy Head & Neck Cancer Symptom Index - 10 Item Version LEARN MORE NFHNSI-22 National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy Head & Neck Cancer Symptom Index - 22 Item Version LEARN MORE FACT-HN Functional Assessment of Cancer Therapy - Head & Neck LEARN MORE

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PRAI Patient-Reported Arthralgia Inventory For patients with arthralgia LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview Developed in conjunction with Vanderbilt University, the 16-item Patient-Reported Arthralgia Inventory (PRAI) was designed to measure arthralgia severity in 16 joints in the context of a longitudinal cohort study to assess aromatase inhibitor-associated arthralgia in breast cancer survivors and arthralgia in postmenopausal women without breast cancer. MEASURE NAME: Patient-Reported Arthralgia Inventory (PRAI) VERSION: 2 NUMBER OF ITEMS: 16 PATIENT POPULATION: Patients 18 years and older with arthralgia RECALL PERIOD: Past 7 days RESPONSE SCALE: 10 point rating scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: None TIME FOR COMPLETION: Not available SCORING: Manual scoring template RELATED MEASURES: FACT-G , FACT-G7 , FACT-BP DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the PRAI can be obtained when licensing the measure. Users are not permitted to translate the PRAI without prior permission from FACIT.org. Permission may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor of the PRAI. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Castel LD, Wallston KA, Saville BR, Alvarez JR, Shields BD, Feurer ID, Cella D. Validity and reliability of the Patient-Reported Arthralgia Inventory: validation of a newly-developed survey instrument to measure arthralgia. Patient Relat Outcome Meas. 2015 Jul 28;6:205-14. doi: 10.2147/PROM.S47997. PMID: 26251635; PMCID: PMC4524452. LICENSE THIS MEASURE Related Measures Related Measures FACT-G Functional Assessment of Cancer Therapy - General LEARN MORE FACT-G7 Functional Assessment of Cancer Therapy – General – 7 Item Version LEARN MORE FACT-BP Functional Assessment of Cancer Therapy - Bone Pain LEARN MORE

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View all available languages for this measure. BACK FACIT-BTCSQ Languages Dutch English French

View all available languages for this measure. BACK FACT-O Languages Afrikaans Arabic Armenian Bengali Bulgarian Cebuano Chinese – Simplified Chinese – Traditional Croatian Czech Danish Dutch English Estonian Finnish French Georgian German Greek Gujarati Hebrew Hindi Hungarian Indonesian Italian Japanese Kannada Korean Latvian Lithuanian Malay Malayalam Marathi Norwegian Odia Polish Portuguese Romanian Russian Serbian Slovak Slovene Spanish Swedish Tagalog Tamil Telugu Thai Turkish Ukrainian Urdu Vietnamese

View all available languages for this measure. BACK FHNSI Languages Afrikaans Arabic Chinese - Simplified Chinese - Traditional Czech Danish Dutch English Estonian Farsi French German Greek Gujarati Hebrew Hindi Italian Japanese Kannada Korean Latvian Lithuanian Malay Malayalam Marathi Norwegian Polish Portuguese Romanian Russian Slovak Spanish Swedish Tagalog Tamil Telugu Thai Turkish Urdu Zulu

peds FAACT-10 Pediatric Functional Assessment of Anorexia/Cachexia Treatment – 10 item version Pediatric Functional Assessment of Anorexia/Cachexia Treatment – 10 item version LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview Below are the details for the peds FAACT measure: MEASURE NAME: Pediatric Functional Assessment of Anorexia/Cachexia Treatment – 10 item version VERSION: 2 NUMBER OF ITEMS: 10 PATIENT POPULATION: Pediatric cancer patients 8-18 years old RECALL PERIOD: Past 7 days RESPONSE SCALE: 5 point Likert-type scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: Not available TIME FOR COMPLETION: Less than 5 minutes SCORING: Manual scoring template, some items are reverse scored. Total scores possible. RELATED MEASURES: peds FACT-Br , peds FACIT-F , peds FAACT DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the peds FAACT-10 can be obtained by registering for permission. Users are not permitted to translate the peds FAACT-10 without permission from FACIT.org. Permission from FACIT.org to translate the peds FAACT-10 may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 1996; 5: 309-320. Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232. Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85. Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191. LICENSE THIS MEASURE Related Measures Related Measures peds FACT-Br Pediatric Functional Assessment of Chronic Illness Therapy – Brain LEARN MORE peds FACIT-F Pediatric Functional Assessment of Chronic Illness Therapy – Fatigue LEARN MORE peds FAACT Pediatric Functional Assessment of Anorexia/Cachexia Treatment LEARN MORE

View all available languages for this measure. BACK FACT-Th18 Languages Arabic Bengali Bulgarian Chinese - Simplified Chinese - Traditional Czech Danish Dutch English Finnish French German Greek Gujarati Hebrew Hindi Hungarian Italian Japanese Kannada Korean Lithuanian Malayalam Marathi Norwegian Polish Portuguese Punjabi Romanian Russian Slovak Spanish Swedish Tamil Telugu Thai Turkish Ukrainian

FACT-Th11 Functional Assessment of Cancer Therapy - Thrombocytopenia 11 Item Version For patients with Thrombocytopenia LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview Below are the details for the FACT-Th11 measure: MEASURE NAME: Functional Assessment of Cancer Therapy - Thrombocytopenia 11 Item Version (FACT-Th11) VERSION: 4 NUMBER OF ITEMS: 38 PATIENT POPULATION: Cancer patients 18 and older with thrombocytopenia RECALL PERIOD: Past 7 days RESPONSE SCALE: 5 point Likert-type scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: Physical Well-Being, Social/Family Well-Being, Emotional Well-Being, Functional Well-Being, Thrombocytopenia Subscale TIME FOR COMPLETION: 10-15 minutes SCORING: Manual scoring template, some items are reverse scored. Subscale scores, total scores and TOI scores available. SAS/SPSS algorithms available. RELATED MEASURES: FACT-Th6 , FACT-Th18 , FACT-G DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the FACT-Th11 can be obtained by registering for permission. Users are not permitted to translate the FACT-Th11 without permission from FACIT.org. Permission from FACIT.org to translate the FACT-Th11 may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 1996; 5: 309-320. Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232. Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85. Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191. LICENSE THIS MEASURE Related Measures Related Measures FACT-Th6 Functional Assessment of Cancer Therapy - Thrombocytopenia 6 Item Version LEARN MORE FACT-Th18 Functional Assessment of Cancer Therapy - Thrombocytopenia 18 Item Version LEARN MORE FACT-G Functional Assessment of Cancer Therapy - General LEARN MORE

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