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BACK FACT-P Languages Afrikaans Arabic Bengali Bulgarian Cebuano Chinese – Simplified Chinese – Traditional Croatian Czech Danish Dutch English Estonian Farsi Finnish French Georgian German Greek Gujarati Hebrew Hiligaynon Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Korean Latvian Lithuanian Malay Malayalam Marathi Norwegian Odia Polish Portuguese Punjabi Romanian Russian Sepedi Serbian Sesotho Slovak Slovene Spanish Swedish Tagalog Tamil Telugu Thai Turkish Ukrainian Urdu Vietnamese Xhosa Zulu

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FACIT-CNI-NTX Functional Assessment of Chronic Illness Therapy – Calcineurin Inhibitor Neurotoxicity For patients receiving calcium inhibitor treatment LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview Below are the details for the FACIT-CNI-NTX measure: MEASURE NAME: Functional Assessment of Chronic Illness Therapy – Calcineurin Inhibitor Neurotoxicity (FACIT-CNI-NTX) VERSION: 1 NUMBER OF ITEMS: 8 PATIENT POPULATION: Patients 18 and older receiving calcium inhibitor treatment RECALL PERIOD: Past 7 days RESPONSE SCALE: 5 point Likert-type scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: CNI-NTX scale TIME FOR COMPLETION: Less than 5 minutes SCORING: Manual scoring template, some items are reverse scored. RELATED MEASURES: FACT/GOG-NTX-4 , FACT/GOG-NTX , FACT/GOG-NTX-12 DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the FACIT-CNI-NTX can be obtained by registering for permission. Users are not permitted to translate the FACIT-CNI-NTX without permission from FACIT.org. Permission from FACIT.org to translate the FACIT-CNI-NTX may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 1996; 5: 309-320. Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232. Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85. Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191. LICENSE THIS MEASURE Related Measures Related Measures FACT/GOG-NTX-4 Functional Assessment of Cancer Therapy/Gynecologic Oncology Group - Neurotoxicity 4 Item Version LEARN MORE FACT/GOG-NTX Functional Assessment of Cancer Therapy/Gynecologic Oncology Group – Neurotoxicity LEARN MORE FACT/GOG-NTX-12 Functional Assessment of Cancer Therapy/Gynecologic Oncology Group – Neurotoxicity 12 Item Version LEARN MORE

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FACT-Th18 Functional Assessment of Cancer Therapy - Thrombocytopenia 18 Item Version For patients with Thrombocytopenia LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview Below are the details for the FACT-Th18 measure: MEASURE NAME: Functional Assessment of Cancer Therapy - Thrombocytopenia 18 Item Version (FACT-Th18) VERSION: 4 NUMBER OF ITEMS: 45 PATIENT POPULATION: Cancer patients 18 and older with thrombocytopenia RECALL PERIOD: Past 7 days RESPONSE SCALE: 5 point Likert-type scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: Physical Well-Being, Social/Family Well-Being, Emotional Well-Being, Functional Well-Being, Thrombocytopenia Subscale TIME FOR COMPLETION: 10-15 minutes SCORING: Manual scoring template, some items are reverse scored. Subscale scores, total scores and TOI scores possible. SAS/SPSS algorithms available. RELATED MEASURES: FACT-Th6 , FACT-Th11 , FACT-G DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the FACT-Th18 can be obtained by registering for permission. Users are not permitted to translate the FACT-Th18 without permission from FACIT.org. Permission from FACIT.org to translate the FACT-Th18 may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 1996; 5: 309-320. Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232. Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85. Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191. LICENSE THIS MEASURE Related Measures Related Measures FACT-Th6 Functional Assessment of Cancer Therapy - Thrombocytopenia 6 Item Version LEARN MORE FACT-Th11 Functional Assessment of Cancer Therapy - Thrombocytopenia 11 Item Version LEARN MORE FACT-G Functional Assessment of Cancer Therapy – General LEARN MORE

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FACT-ES Functional Assessment of Cancer Therapy - Endocrine Symptoms For patients with Endocrine Symptoms LICENSE THIS MEASURE Overview Language Availability Licensing Selected References Related Measures Overview Overview Below are the details for the FACT-ES measure: MEASURE NAME: Functional Assessment of Cancer Therapy - Endocrine Symptoms (FACT-ES) VERSION: 4 NUMBER OF ITEMS: 46 PATIENT POPULATION: Cancer patients 18 years and older receiving endocrine treatments RECALL PERIOD: Past 7 days RESPONSE SCALE: 5 point Likert-type scale DATA COLLECTION: Paper and electronic ADMINISTRATION: Self-administration and interview when applicable SUBSCALE DOMAINS: Physical Well-Being, Social/Family Well-Being, Emotional Well-Being, Functional Well-Being, Endocrine Symptom Subscale TIME FOR COMPLETION: 10-15 minutes SCORING: Manual scoring template, some items are reverse scored. Subscale scores, total scores and TOI scores possible. SAS/SPSS algorithms available. RELATED MEASURES: FACT-B , NFBSI-16 , FBSI-8 DOWNLOAD MEASURE IN ENGLISH DOWNLOAD SCORING DOCUMENT Language Availability Available translations of the FACT-ES can be obtained by registering for permission. Users are not permitted to translate the FACT-ES without permission from FACIT.org. Permission from FACIT.org to translate the FACT-ES may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system. Please contact us for more information. VIEW AVAILABLE LANGUAGES Language Availability Licensing Licensing Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained. Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use. To license an available version of this measure for commercial or non-commercial use, please complete our registration form . All of the information provided in the form will be kept strictly confidential. For questions, please contact us . LICENSE THIS MEASURE Selected References Selected References Fallowfield, L. J., Leaity, S. K., Howell, A., Benson, S. & Cella, D. Assessment of quality of life in women undergoing hormonal therapy for breast cancer: Validation of an endocrine symptom subscale for the FACT-B. Breast Cancer Research and Treatment 1999; 55: 189-199. Fallowfield, L., Atkins, L., Catt, S., Cox, A., Coxon, C., Langridge, C., Morris, R., & Price, M. Patients’ preference for administration of endocrine treatments by injection or tablets: results from a study of women with breast cancer. Annals of Oncology 2006; 17(2): 205–210. doi: 10.1093/annonc/mdj044. Fallowfield, L., Bliss, J., Porter, L., Price, M., Snowdon, C., Jones, S., Coombes, C., & Hall, E. Quality of Life in the Intergroup Exemestane Study: A Randomized Trial of Exemestane Versus Continued Tamoxifen After 2 to 3 Years of Tamoxifen in Postmenopausal Women With Primary Breast Cancer. Journal of Clinical Oncology 2006; 24(6): 910-917. doi: 10.1200/JCO.2005.03.3654. Hershman DL, Neugut AI, Moseley A, Arnold KB, Gralow JR, Henry NL, Hillyer GC, Ramsey SD, Unger JM. Patient Reported Outcomes and Long-Term Non-Adherence to Aromatase Inhibitors. J Natl Cancer Inst. 2021 Feb 25:djab022. doi: 10.1093/jnci/djab022. Epub ahead of print. PMID: 33629114. Hickey, M., Marino, J., Braat, S., Wong, S. A randomized, double-blind, crossover trial comparing a silicone versus water-based lubricant for sexual discomfort after breast cancer. Breast Cancer Research and Treatment 2016; 158:79–90. doi: 10.1007/s10549-016-3865-1. Marino, J., Saunders, C., Emery, L., Green, H., Doherty, D., & Hickey, M. Nature and severity of menopausal symptoms and their impact on quality of life and sexual function in cancer survivors compared with women without a cancer history. Menopause 2014; 21(3): 267-274. doi: 10.1097/gme.0b013e3182976f46. Marino J,., Saunders, C., Emery. L., Green, H., Doherty, D., & Hickey, M. How does adjuvant chemotherapy affect menopausal symptoms, sexual function, and quality of life after breast cancer? Menopause 2016; 23(9): 1000-1008. doi: 10.1097/GME.0000000000000664. Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Quality of Life Research 1996; 5: 309-320. Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232. Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85. Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191. LICENSE THIS MEASURE Related Measures Related Measures FACT-B Functional Assessment of Cancer Therapy – Breast LEARN MORE NFBSI-16 National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy Breast Cancer Symptom Index - 16 Item Version LEARN MORE FBSI-8 FACT Breast Symptom Index LEARN MORE

BACK PROMIS SF v1.0-Dyspnea-Functional Limitations 5b Languages Arabic Afrikaans Bengali Bulgarian Chinese - Simplified Chinese - Traditional Czech Danish Dutch English Finnish French German Greek Gujarati Hebrew Hindi Hungarian Italian Japanese Kannada Korean Malay Malayalam Marathi Norwegian Polish Portuguese Punjabi Romanian Russian Serbian Slovak Slovene Spanish Swedish Tagalog Tamil Telugu Thai Turkish Ukrainian Urdu Xhosa Zulu